abstract：:The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the freque...

journal_title：Endokrynologia Polska

authors： Drozdzowska B

更新日期：2011-01-01 00:00:00

abstract：:Osteoporosis is a chronic disease of the osseous system characterised by decreased strength of bone tissue, which in turn leads to increased fracture risk. It has been demonstrated that osteoporosis affects more than 30% of women after the menopause (WHO, 1994). However, the disease is also observed in men. The primar...

journal_title：Endokrynologia Polska

authors： Sewerynek E,Stuss M

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Considering the high prevalence of congenital hypothyroidism (CH) in Isfahan, it seems that it is necessary to investigate the aetiology of the disorder and its related factors. The aim of this study was to determine the aetiology of CH among children in Isfahan province. MATERIAL AND METHODS:In this cros...

journal_title：Endokrynologia Polska

authors： Hoseini M,Hekmatnia A,Hashemipour M,Basiratnia R,Omidifar N,Rezazade A,Koohi R

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:Poorly differentiated thyroid carcinoma (PDTC, insular carcinoma) occurs rarely. It is described with more aggressive behaviour, poorer prognosis, and higher mortality than well differentiated thyroid carcinoma (WDTC). The aim of this study was to evaluate the clinical course of patients with PDTC, in addi...

journal_title：Endokrynologia Polska

authors： Walczyk A,Kowalska A,Sygut J

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:To evaluate the clinical profile of BIAsp 30 (30% soluble insulin aspart, 70% protamine-crystallized insulin aspart) (NovoMix®)30) in type 2 diabetes patients in routine clinical practice in Iran. MATERIAL AND METHODS:IMPROVE™ was a 26-week, multinational, open-label, non-randomized study in patients with...

journal_title：Endokrynologia Polska

authors： Esteghamati A,Rajabian R,Amini M,Bahrami A,Khamseh ME,Afkhami-Ardekani M,Rizi EP

更新日期：2010-07-01 00:00:00

abstract：INTRODUCTION:Aim of the study was present personal observations connected with the management of patients referred to surgical treatment for secondary hyperparathyroidism (SHT) or tertiary hyperparathyroidism (THT), and to assess immediate results of such management. MATERIAL AND METHODS:A total of 175 patients aged 2...

journal_title：Endokrynologia Polska

authors： Buła G,Koziołek H,Niemiec A,Gawrychowski J

更新日期：2010-05-01 00:00:00

abstract：:The introduction of sonographic imaging has revolutionized the diagnostics of thyroid pathologies. Nowadays, thyroid ultrasound examination has become an essential part of routine thyroid gland evaluation. Although one of the greatest advantages of this examination lies in its simplicity, it requires a solid theoretic...

journal_title：Endokrynologia Polska

authors： Ruchała M,Szczepanek E

更新日期：2010-05-01 00:00:00

abstract：:A case of POF in a 31-year-old woman with karyotype 47,XXX. The aim of the study was to discuss a case of POF in a 31-year-old patient with polysomy 47,XXX. The described karyotype is not usually associated with this characteristic physical phenotype. In some rare cases, menstrual disorders, sterility, secondary ameno...

journal_title：Endokrynologia Polska

authors： Skałba P,Cygal A,Gierzyńska Z

更新日期：2010-03-01 00:00:00

abstract：:The World Health Organization (WHO) issued a recommendation (Technical Consultation: Paris 2006, Luxembourg 2007) that salt consumption, as a risk factor for hypertension, atherosclerosis, myocardial infarction, stroke, and select cancers, should be restricted. The European Commission looked to adhere to this recommen...

journal_title：Endokrynologia Polska

authors： Szybiński Z,Jarosz M,Hubalewska-Dydejczyk A,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Traczyk I,Stoś K

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Ghrelin is a polypeptide hormone secreted mainly by the stomach cells, stimulating food intake and growth hormone release. Decreased plasma ghrelin concentration was found in obese subjects. Clinical and experimental data suggest that ghrelin also exerts a blood pressure lowering property. The influence of...

journal_title：Endokrynologia Polska

authors： Skoczylas A,Adamczak M,Chudek J,Wiecek A

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Patients with Addison's disease experience many somatic and psychic changes, which decrease their quality of life. The aim of the study was to evaluate the "psychological equipment" of these patients to cope with stress connected with this chronic disease and the challenge of constant treatment. MATERIAL ...

journal_title：Endokrynologia Polska

authors： Warmuz-Stangierska I,Baszko-Błaszyk D,Sowiński J

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The aim of the study was to estimate the influence of nicotine on thyroid volume according to patients' sex. MATERIAL AND METHODS:A group of 160 patients with thyroid disorders in their past medical history was examined. Patients were divided into two groups: Group A contained 50 patients with goiter, whe...

journal_title：Endokrynologia Polska

authors： Gierach M,Gierach J,Junik R

更新日期：2009-11-01 00:00:00

abstract：:The paper presents actual data concerning osteoporotic fractures (definitions, causes, epidemiologic and clinical data, consequences, treatment) particulary data about the most common fractures (distal forearm, vertebral and proximal hip fractures). ...

journal_title：Endokrynologia Polska

authors： Drozdzowska B

更新日期：2009-11-01 00:00:00

abstract：:Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are often used by athletes as doping agents. It is estimated that up to 25% of sportsmen using anabolic-androgenic steroids also take GH. Available data do not confirm the influence of GH or IGF-1 preparations on physical performance improvement. However, th...

journal_title：Endokrynologia Polska

authors： Jóźków P,Medraś M

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The activity of androgen receptor (AR) is modulated by a polymorphic region located within exon 1 its gene and characterizing a variable number of trinucleotide CAG repeats. The length of polymorphic region is inversely correlated with the transactivation function of AR gene. It was showed an ethnic differen...

journal_title：Endokrynologia Polska

authors： Filus A,Medraś M,Kuliczkowska-Płaksej J,Trzmiel-Bira A,Laczmański L,Jedrzejuk D

更新日期：2009-07-01 00:00:00

abstract：INTRODUCTION:The recent investigations point out the significant role of oxidative stress in the development of thyroid gland disease. The present study was designed to investigate the variation of oxidative stae in women with non-autoimmunological subclinical hyperthyroidism. MATERIAL AND METHODS:The study was conduc...

journal_title：Endokrynologia Polska

authors： Rybus-Kalinowska B,Zwirska-Korczala K,Kalinowski M,Kukla M,Birkner E,Jochem J

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:Recently, a new fracture risk-assessment calculator (FRAX) has been introduced. The aim of this study was to assess its usefulness for the re-assessment of fracture risk in obese patients and re-assignment to treatment. MATERIAL AND METHODS:350 obese female patients were included. In all of them, 10-year ...

journal_title：Endokrynologia Polska

authors： Franek E,Wichrowska H,Gozdowski D,Puzianowska-Kuźnicka M

更新日期：2009-03-01 00:00:00

abstract：INTRODUCTION:Children's obesity is a known health problem in the world and is a strong predictor of obesity in adulthood which increases the incidence of related diseases such as metabolic syndrome. According to the MONIKA project by the World Health Organization (WHO), Iran is one of the seven countries with a high ra...

journal_title：Endokrynologia Polska

authors： Adibi A,Kelishadi R,Beihaghi A,Salehi H,Talaei M

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Generally, squamous cell carcinoma carries a poor prognosis because of its tendency to local invasion and subsequent metastasis, which is mediated by multiple factors and angiogenesis. Hepatocyte growth factor (HGF) is a potent mitogen for epithelial cells and regulates cell proliferation and migration and...

journal_title：Endokrynologia Polska

authors： Borgiel-Marek H,Kajdaniuk D,Niedzielska I,Kos-Kudła B,Tarabura-Dragon J,Marek B

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:The clinical usefulness of baroreflex sensitivity (BRS) in the early detection of autonomic dysfunction in patients with diabetes is not well established. The aim of the study was the evaluation of BRS in subjects with type 1 diabetes with and without cardiovascular autonomic neuropathy (CAN). MATERIAL AN...

journal_title：Endokrynologia Polska

authors： Kamińska A,Tafil-Klawe M,Smietanowski M,Bronisz A,Ruprecht Z,Klawe J,Junik R

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:Secretory products from adipocytes may contribute to deterioration in glycaemic control and increased insulin resistance (IR). Retinol-binding protein 4 (RBP-4) may increase IR in mice, with elevated levels in insulin-resistant mice and humans with obesity and type 2 diabetes. However, the mechanisms regul...

journal_title：Endokrynologia Polska

authors： Lewandowski KC,Basinska-Lewandowska M,Bieńkiewicz M,Randeva HS,Lewiński A

更新日期：2008-07-01 00:00:00

abstract：:The authors present numerous historical descriptions of persons who might suffered from gigantism or acromegaly. The oldest medical data of patients, initial attempts of causal neurosurgical treatment, history of growth hormone, insulin-like growth factor-1, growth hormone releasing hormone and somatostatin discovery ...

journal_title：Endokrynologia Polska

authors： Kałuzny M,Bolanowski M

更新日期：2008-05-01 00:00:00

abstract：:Anorexia nervosa is an eating disorder characterized by conscious restriction of food intake, which causes numerous metabolic and hormonal disorders. Knowledge of these changes is important due to growing morbidity and mortality of anorexia. Treatment is difficult and requires cooperation of a group of specialists, in...

journal_title：Endokrynologia Polska

authors： Nogal P,Lewiński A

更新日期：2008-03-01 00:00:00

abstract：:We have recently observed an increased interest in gastro-entero-pancreatic neuroendocrine tumors (GEP NET). They are rare cancer types and therefore collaborative effort of specialists in various disciplines of medicine is necessary to work out the diagnostic and therapeutic guidelines. In this publication we present...

journal_title：Endokrynologia Polska

authors： Kos-Kudła B,Bolanowski M,Handkiewicz-Junak D,Jarzab B,Królicki L,Krzakowski M,Kunikowska J,Nasierowska-Guttmejer A,Nowak A,Rydzewska G,Starzyńska T,Szawłowski A,oraz Pozostali Uczestnicy Konferencji Okragłego Stołu.

更新日期：2008-01-01 00:00:00

abstract：:Arteriovenous carotid-cavernous fistula is an abnormal connection between the dural branches of carotid artery or vertebral artery and the dural sinuses. Its clinical manifestations can resemble the crucial signs of thyroid orbitopathy, an inflammatory disorder of the orbit associated with Graves' disease. Therefore, ...

journal_title：Endokrynologia Polska

authors： Reniewska B,Mulak M,Słowiński K,Rusiecka-Ziółkowska J

更新日期：2007-11-01 00:00:00

abstract：:The process of angiogenesis in a heart muscle is a way of providing the ischaemic myocardium with oxygen and nutritive ingredients. This natural process called therapeutic angiogenesis has been tried in the treatment of patients with coronary artery disease mainly. It has been seen as a chance of an effective benefici...

journal_title：Endokrynologia Polska

authors： Jośko J,Ratman K,Ratman RM

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Symptoms of precocious puberty (PP) in children always arouse anxiety in their parents. Many children with PP are being hospitalized for the detailed diagnostic work-up. The aim of our study was to analyze the frequency of the variants of PP in children referred to our department. MATERIAL:Retrospective a...

journal_title：Endokrynologia Polska

authors： Januszek-Trzciakowska A,Kalina-Faska B,Kalina M,Zachurzok-Buczyńska A,Gawlik A,Małecka-Tendera E

更新日期：2007-07-01 00:00:00

abstract：:Acromegaly can be treated with several medical modalities. The growth hormone (GH) receptor antagonist pegvisomant, in particular, is able to reduce serum insulin-like growth factor I (IGF-I) concentrations to almost any desired level. Along with this important achievement come other practical issues. The most importa...

journal_title：Endokrynologia Polska

authors： van der Lely AJ

更新日期：2007-07-01 00:00:00

abstract：:We present a case of a woman with unique multisystem disorder--POEMS syndrome and endocrine abnormalities coexisting with it. The POEMS acronym comprises the dominant features: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein (M protein), skin changes. Association between plasma cell dyscrasia and poly...

journal_title：Endokrynologia Polska

authors： Lizis-Kolus K,Kowalska A,Nowakowska-Domagała M

更新日期：2007-05-01 00:00:00

abstract：:There is a growing number of diseases which prevalence can be associated with vitamin D deficiency. The link between low cholecalciferol concentration and bone diseases is well established, however there is also data suggesting that it may influence development and progression of different cancers and autoimmune disea...

journal_title：Endokrynologia Polska

authors： Kuryłowicz A,Bednarczuk T,Nauman J

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:In order to be effective, treatment for osteoporosis must be long-term. Unfortunately, according to clinical trials and clinical practice the most frequent cause of patient resignation from the treatment is adverse reactions to the medications. In the case of bisphosphonates they are most frequently connec...

journal_title：Endokrynologia Polska

authors： Jastrzebski Z,Napiórkowska L,Pykało R

更新日期：2007-01-01 00:00:00

abstract：:The basic data on hyperprolactinemia (i.e. an excess of PRL above a reference laboratory's upper limits), the most common endocrine disorder of the hypothalamic-pituitary axis are given in this review. The following issues are discussed: regulation of prolactin (Prl) secretion, definition of hyperprolactinemia, its et...

journal_title：Endokrynologia Polska

authors： Karasek M,Pawlikowski M,Lewiński A

更新日期：2006-11-01 00:00:00

abstract：:One severe aplastic anaemia case who presented autoimmune thyroid disease after allogeneic bone marrow transplantation (alloBMT) is described. A 19 year old Polish girl developed Graves' hyperthyroidisms 19 months after allogeneic BMT for severe aplastic anaemia (SAA) donated from her brother. Her serum was positive f...

journal_title：Endokrynologia Polska

authors： Jakubas B,Kostecka-Matyja M,Darczuk A,Gil J

更新日期：2006-09-01 00:00:00

abstract：INTRODUCTION:Estimation of malignancy in thyroid follicular neoplasms is a common diagnostic problem, thus revealing of differences in expression of some antigens in both benign and malignant lesions seems to be essential. The aim of this study is to evaluate the immunohistochemical expression of CD15, galectin-3 and H...

journal_title：Endokrynologia Polska

authors： Bogdańska M,Górnicka B,Ziarkiewicz-Wróblewska B,Koperski L,Morton M,Wasiutyński A

更新日期：2006-07-01 00:00:00

abstract：INTRODUCTION:Since the effect of pre-therapeutic scintigraphy on the outcome of DTC treatment is debated, we evaluated factors affecting the effectiveness of (131)I therapy with respect to the delay between diagnostic scintigraphy and the application of radioiodine. MATERIAL AND METHODS:In the studied group of 60 pati...

journal_title：Endokrynologia Polska

authors： Bałdys-Waligórska A,Buziak-Bereza M,Huszno B,Wilczak A

更新日期：2006-07-01 00:00:00

abstract：:Among genetic alterations most important for the initiation of papillary thyroid carcinoma (PTC) is mutation T1799A in the BRAF gene which is the most frequent event (54.5%) in this type of thyroid cancer. It is seen in all stages, from microcarcinoma through clinically overt disease to anaplastic cancer. It has been ...

journal_title：Endokrynologia Polska

authors： Rusinek D,Gubała E

更新日期：2006-07-01 00:00:00

abstract：:We describe a 37 year-old woman case of latent autoimmune diabetes in adults (LADA). She was presented with unfounded weight loss. The diagnosis of diabetes mellitus was established on twice plasma glucose measurements above 200 mg/dl. In other routine biochemical examinations we did not observe dehydratation, electro...

journal_title：Endokrynologia Polska

authors： Szepietowska B,Szelachowska M,Górska M

更新日期：2006-05-01 00:00:00

abstract：:The authors present the current knowledge on the intracellular mechanisms of thyroid hormone action in the cardiomyocytes. Many of the clinical manifestations of thyroid diseases are due to the ability of thyroid hormone to alter cardiovascular hemodynamics. Triiodothyronine affects the hemodynamic state mainly by its...

journal_title：Endokrynologia Polska

authors： Gatnar A,Marek B,Pakuła D,Kajdaniuk D,Kos-Kudła B,Borgiel-Marek H,Gnot R,Pakuła P,Pawłowska M

更新日期：2006-03-01 00:00:00

abstract：INTRODUCTION:Fine needle aspiration biopsy (FNAB) of the thyroid nodules generally allows to make the diagnosis and to choose the proper clinical management. In about 10% of cases cytopathologic features do not differentiate unequivocally benign and malignant lesions. In these cases the cytopathologic diagnosis of foll...

journal_title：Endokrynologia Polska

authors： Ponikiewska D,Szcześniak-Kłusek B,Stobiecka E,Jaworska M,Lange D

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The introduction of the DICOM format in all diagnostic imaging devices allowed co-registering SPECT, CT, MR and other types of biomedical imaging. Fusion can be performed by dedicated hybrid devices or by means of software. The fusion algorithm consists of two steps: coregistration and simultaneous visuali...

journal_title：Endokrynologia Polska

authors： d'Amico A,Szczucka K,Borys D,Gorczewski K,Steinhof K

更新日期：2006-01-01 00:00:00